Cleaning your dentures regularly is essential to maintain their appearance and prevent the build-up of bacteria and plaque. After removing, rinse your dentures thoroughly with warm running water. With a soft bristle brush and mild soap brush all surfaces, including teeth, gums, and the roof of your mouth. Soak your dentures in a denture cleanser for the recommended time on the package. Store your dentures in a clean, dry container. Don't forget to clean your mouth also, brushing your gums, tongue and the roof of your mouth.